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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAG
All Species:
40.61
Human Site:
T145
Identified Species:
68.72
UniProt:
P61981
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61981
NP_036611.2
247
28303
T145
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Chimpanzee
Pan troglodytes
XP_519163
321
36086
T219
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001111955
233
26714
S132
A
S
G
E
K
K
N
S
V
V
E
A
S
E
A
Dog
Lupus familis
XP_546936
343
38553
T241
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
T142
A
S
G
E
N
K
Q
T
T
V
S
N
S
Q
Q
Rat
Rattus norvegicus
P61983
247
28284
T145
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505266
247
28347
S145
A
A
G
E
K
K
N
S
V
V
E
A
S
E
A
Chicken
Gallus gallus
Q5F3W6
247
28212
T145
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Frog
Xenopus laevis
Q6PCG0
247
28255
T145
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Zebra Danio
Brachydanio rerio
Q6PC29
247
28216
A145
A
T
G
E
K
R
A
A
V
V
E
S
S
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
T143
A
T
G
D
A
R
N
T
V
V
D
D
S
Q
T
Honey Bee
Apis mellifera
XP_391841
247
28058
A142
A
T
G
E
T
R
N
A
V
V
D
D
S
Q
K
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
S142
A
S
G
D
D
R
N
S
V
V
E
K
S
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
K145
S
S
G
D
A
R
E
K
A
T
N
S
S
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
78.1
67.3
N.A.
76.5
100
N.A.
80.1
99.5
98.7
95.9
N.A.
73.3
77.3
74.5
N.A.
Protein Similarity:
100
76.9
84.6
69.3
N.A.
86.6
100
N.A.
87
99.5
99.1
98.3
N.A.
83.8
85.4
85.4
N.A.
P-Site Identity:
100
100
60
100
N.A.
40
100
N.A.
60
100
100
93.3
N.A.
53.3
60
46.6
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
73.3
100
N.A.
80
100
100
93.3
N.A.
73.3
73.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
57.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
8
0
0
15
0
50
15
8
0
0
15
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
22
8
0
0
0
0
0
15
15
0
0
0
% D
% Glu:
0
0
0
79
0
0
8
0
0
0
72
0
0
65
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
65
22
0
8
0
0
0
8
0
0
58
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
36
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
29
15
% Q
% Arg:
0
0
0
0
0
79
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
29
0
0
0
0
0
22
0
0
8
58
100
0
0
% S
% Thr:
0
65
0
0
8
0
0
58
8
8
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
86
93
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _